Believer,
In addition to MM's comments, here are some rules about "a lot of" and "lots of".
(1) Both "a lot of" and "lots of" are used with singular uncountable and plural nouns. Most importantly, they are not used with singular countable nouns.
For example, 'A lot of pencil is on the table' is wrong since 'pencil' is a singular countable noun.
(2) The verb of a sentence is not decided by 'a lot of' or 'lots of', rather the verb is decided by the noun that follows 'of'.
For example,
A lot of pencils are on the table (Subject -Plural countable nouns Verb-are)
A lot of time is spent on Salt Lake River project (Subject -Uncountable noun Verb-is)
(3) Both 'a lot of' and 'lots of' are normally avoided in formal writing. If you want to use 'many' or 'much' instead of 'a lot of' and 'lots of', use 'many' with countable nouns and 'much' with uncountable nouns.