Dear all,
I am planning to apply for PhD in life science, and written my SOP, please help me if any corrections need to be incorporated like grammar, sentence, etc.

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“Is it possible for human to understand and overcome infectious diseases completely?” My interest in infectious disease and biomedical research gained fresh impetus during my postgraduate studies at St. Aloysius. My post graduation research thesis, “studies on Urease inhibitor; effects on Urease producing bacteria and cytotoxic effects on mammalian cells” inspired me to think science on every aspect in life. The focus was on elucidating phytochemical Urease inhibitor for understanding the significance of the enzyme inhibition, and possibility of feature implementation in treatment of infectious disease like Ammonia encephalopathy, peptic ulceration, urinary and gastrointestinal tract infection and urolithiasis.

 

The sharing of ideas and new findings has always been a vital part of my postgraduate life. Presentations were a perfect opportunity for me to explore beyond the syllabus and were instrumental in giving me a competitive edge over my peers. I relish a chance to indulge my creative side and gaining a deeper understanding of my work in the process ‘make presentations a good bargain’! I enjoy diving into a flood of data, picking out relevant information and delivering it all to an appreciative audience! The dynamic nature of scientific research was revealed to me as I worked on my presentations. I exchanged many thoughts and came across various achievements in the biomedical, pathology and related fields during presenting my work in national and international symposiums and seminars, it inspired me to achieve my goal in this field.

 

As my work progressed it raised a few questions in my mind. How pathogens sense the environment? How exactly immune system respond for these pathogens? Is susceptibility to such disease is driven by certain specificities like individuality, race and topological boundaries?

 

Once out of college, I was thirsting to put into practice all my postgraduate education. Joining as research associate in “***”, a pharma company with vision of innovative research for biopharmaceuticals, bionutritionals and therapeutic drug gave me the perfect opportunity to glimpse at the career I am entering. I worked in different projects but the most interesting one were project on Japanese encephalitis virus, to clone the soluble region of the JEV ‘E’ protein, into a microbial system with view to express the same for detection of the infection, which is endemic to South-east Asia, several regions of India where one fifth succumbs to the disease and a high proportion of survivors have serious neurologic and psychiatric consequences. Another project to express the human ACC2del26 in an insect cell line, to use it as a potential drug target for the treatment of metabolic syndrome, including obesity, diabetes type 2 and dyslipidemia. As my professional life has progressed, my resolve to have a career in research has strengthened.

 

Besides opening up the world of scientific research to me, my 2 years of academic research and 2.6 years of professional experiences here have taught me that mistakes do not always have to hold you back, and often take you closer to your goal. Things often look easy to do at first glance, but a lot of hard work is involved in making them seem that way. After standardizing some protocols myself, I now understand the kind of effort that goes into developing the techniques that make my work so much easier.

 

While reading about the research being done in the biomedical, infectious disease field at *** University, I have come across work that can provide answers to my questions I want to continue my research which will help me gain a deeper understanding of this field to answer my questions.

 

My life experiences have molded me in to a hardworking and what I would call an "unflappable" person. My future goals include establishing a career in research which could really be novel and implementable. Scientific research has its origins in a very fundamental human character; curiosity. It is very important though, to ask the right question. Research in Biomedical and pathological field at *** University has raised many relevant questions; I would like to be one of the people working towards the answers and believe that I have abilities, motivation and competence to achieve it.    

Thank you all