Hi,
"Now Annie, all of 12, has always been precocious, but she’s
got a good head on her shoulders and I like it when she uses it..."
Do that (all of 12) statement have "despite" meaning?
Yes, broadly speaking.
"Now Annie, despite being only 12, has always been precocious, but she’s
got a good head on her shoulders and I like it when she uses it..."
Clive