The meaning of "out of" and "fair", thank you!

I read a passage as follows:

“We are talking about middle-class Americans — people who are not poor enough to qualify for Medicaid or charity care. They’re working-class folks that own a home, have a small business, may have a college savings account saved up for their children," he says.

People like Lisa and Scott Starbuck. The Knoxville, Tenn., couple was making about $50,000 a year, before taxes, in the computer-consulting business they run out of their home. A decade ago, they were downsized out of corporate jobs where they had health insurance. Lisa got insurance on her own, but Scott couldn't afford insurance after he was diagnosed with diabetes.

"Is it fair to say you were hoping against hope that the diabetes would get under control and there wouldn’t be any other illness?" Rather asks.

I understand the passage, but I have two questions:

1. What is downsized out of corporate jobs?

2.  Fair is a easy word. But I really can't know the meaning of  Is it fair to say , could you tell me the meaning and use other words.

Thanks a lot!

"Is it fair to say" is also a typical reporter question. The reporter says "Is it fair to say you are hoping for large sales this fall?" and the interviewee say "Yes, that's fair to say" and the reporter writes the story with the person being interviewed as having made the statement "We are hoping for large sales this fall."  It's one of the tricks you learn when doing public affairs that you don't answer those questions directly.

Grammar Geek wrote:

"Is it fair to say" is also a typical reporter question. The reporter says "Is it fair to say you are hoping for large sales this fall?" and the interviewee say "Yes, that's fair to say" and the reporter writes the story with the person being interviewed as having made the statement "We are hoping for large sales this fall."  It's one of the tricks you learn when doing public affairs that you don't answer those questions directly.

Thanks for your explanations.