I think that one obvious difference to be pointed out here is that:
/ɔː/ is a monophthong while /oʊ/ is a diphthong (that is, if you were in fact referring to these symbols)
- The first one (monophthong) mainly consists of only one sound, whereas the second one (diphthong)is actually a combination of two sounds produced with different tongue/mouth settings, connected with a movement of the tongue (tongue glide) – so two different sounds, basically.
- Both sounds require the lips to be more or less rounded, and feel as if they're produced in the back of your mouth.
(Also, in the future, I think you'd better include some form of 'please', 'thank you in advance' or at least a less imperative way of asking your question). There are a lot of outstanding teachers available on this forum who are most willing to help you -- for free. But it's all based on respect.) Try it and you'll see that you will be helped much more promptly next time.
Kind regards
Dokterjokkebrok