Yes.
out of is commonly used for talking about the location of a business. Verbs like
operate and
run are the most usual.
George runs a business out of his garage.
I would like to know how to run a business out of my home.
Operating out of an office in the suburbs, the organization runs various youth clubs and sports activities.
In 1903 the Buick Motor Company moved to Flint to operate out of a new factory.
Note also the emphasis is on the location as a hub of activity, making the expression appropriate for transportation systems.
Diesel railcars operate various trips out of
Kingsville every Sunday.
Fly-with-Us Airlines will operate out of Johnston Air Force Base.
The pirates operate out of a limited number of
ports.
CJ