She hasn't come to visit us since her wedding (on July 7th) > OK
She hasn't come to visit us since she got married > OK
"Since" introduces either a complement referring to a precise moment in the past, or a time clause referring to a precise moment in the past (simple past). In those cases, the main clause is in the present perfect tense.
"Since" can also mean +/- "because". "She won't come with us, since she's sick".
But then it has nothing to do with time, and you don't have to use it with the simple past.