Figure 35-4 shows a designated end of each light and heavy chain, called the variable portion; the remainder of each chain is called the constant portion. The variable portion is different for each specific antibody, and it is this portion that attaches specifically to a particular type of antigen. The constant portion of the antibody determines other properties of the antibody, establishing such factors as antibody diffusivity in the tissues, adherence to specific structures within the tissues, attachment to the complement complex, ease with which the antibodies pass through membranes, and other biological properties of the antibody. A combination of noncovalent and cova-lent bonds (disulfide) holds the light and heavy chains together.

This is a paragraph from Guyton and Hall Textbook of Medical Physiology.

what's the meaning of establishing such factors as in above sentences?  Thanks!
sdasd tontestablishing such factors as
and at the same time determines factors such as