To say I am fed up with you, could you say: I am so full of you?
"I am fed up with you", is an expression that means "I am tired of you".

I have heard people say, "I am full up to here with you", to mean that they
have had too much of someone, so maybe you are right either way?
Students: Are you brave enough to let our tutors analyse your pronunciation?
Thank you so much. I have never heard that expressio before. It's so rewarding to learn a new thing every day.Emotion: wink
You would only say "I am so full of you" if you were a cannibal, but then I'd be dead so I probably wouldn't hear it anyway.