Denise and Denephew

A pregnant woman from Virginia was involved in a car accident and, while in the hospital, she fell into a coma. When she awoke days later, the woman noticed that she was no longer carrying a child, and asked, "Doc, what happened to my baby!"

The doctor replied, "Ma'am, you've had twins! You're the proud mother of a handsome baby boy and a beautiful baby girl. Also, you should know that while you were in a coma, your brother named the children for you."

"Oh, no!" shrieked the woman. "Not my brother! He's not really all together, if you know what I mean!"

The doctor replied, "Well, ma'am, your brother named your daughter Denise."

"Oh, that's no so bad," smiled the woman. Then, hesitantly, she asked, "What's the boy's name?"

The doctor grinned and said, "Denephew."

I can't understand this jok, and don't kow the "denephew" meaning. Who can help me?
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maybe de"nephew"??
Yeah, Denise meant "the niece" and Denephew meant "the nephew".
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The woman's daughter and son are her brother's niece and nephew by relation, respectively. This is simply a play on words--Denise sounds like "the niece" while "Denephew" sounds like "the nephew". The punch line lies in the fact that Denise is a perfectly normal girl's name but Denephew reflects on the brother's lack of intellegence.
Does "He's not really all together" means "He is illiterate" ?

Is "not all together" a slang widely used?
No the phrase should be 'he's not all there' (meaning he is a bit stupid or a bit barmy).
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Denise is pronounced by some as de neice. Some people say de instead of the. Thus denise is the same as the neice.

So denephew is then "the nephew".

The joke is that her brother named his neice "de neice" which doesn't sound too bad as denise, but his stupidity becomes clear when we see that he named his nephew "denephew".

Hope that helps
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