+0
His patience is wearing thin.
His patience is running out.
His patience is pretty at an end.
He's at the end of his tether.
He can't take any more.

Thanks,
+0
He's had enough
He's had it up to here
He's fed up
Comments  
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It took a tolll on me

It took a tolll on me

This has a spelling error and a punctuation error.

how do I say this differently: when business alignment for a project is constant

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Coming to terms with the ending of therapy was highly personally meaningful and loaded with affective tensions, in ways that were not always shared with their therapist.