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Hi everybody,
I am a postgraduate student who is looking for a PhD in Microbiology. I have written a Motivational Letter. As it is the first time I do it and because of my not excellent English I kindly ask you to help me.
Thanks in advance

Dear Dr. XXX

I am writing to express my interest in the PhD position available in the Bacterial Immune Evasion group at the Department of Medical Microbiology in the UMC Utrecht. I took my Master’s Degree in Functional Genomics at the University of Trieste in March 2014, and I am confident my academic background and research experience, would allow me to contribute to gain insight into the biological function of streptococcal polysaccharides in host-pathogen interaction.

In one of my classes, Molecular Biology of the Cell, which was taught by Professor Marco Scocchi, I had the chance to discover the fascinating world of bacterial pathogens. This led me to successfully apply for an Erasmus Placement scholarship that allowed me to spend a 7 month-long training period at the Centre for Biotechnology and Biomedicine in Leipzig which has an international reputation and tradition for scientific and academic excellence in the development of novel antimicrobial compounds to address Gram-negative multi-drug resistance. Under the supervision of Professor Ralf Hoffmann, I was involved in a research project aimed at elucidating proline-rich antimicrobial peptides mechanisms of action and identifying their potential intracelluar targets. The thesis, built upon this project, provided interesting insight into the ability of this class of antimicrobial peptides to kill bacteria by blocking in vivo protein synthesis.

This research experience has reinforced my appreciation for Microbiology with a particular focus on the global threat represented by the bacterial multi-drug resistance. Furthermore, it allowed me to broaden a range of practical and transferable skills relevant to the Biological and Biomedical disciplines, be able to work independently, take initiative to plan and organize daily activities and tasks, and accept responsibility for problems as they arise.

I am very interested in working on host-pathogen interaction for its potential positive impact on the world public human health. With bacterial and emerging infectious diseases becoming potential threats to humans, it is a very promising focus area in antibiotic and vaccine research. I have explored your web page in detail, and it seems like an excellent fit for me because of its emphasis on mechanisms of bacterial pathogenesis. Beside the aim to design more effective pharmacological interventions and vaccine strategies, what I find very attractive is the ambitious aim to explain in details the function of streptococcal polysaccharides, from the elucidation of their biosynthesis pathway to the understanding of their key role played in host-pathogen interaction. At the UMC Utrecht, I will have the great and precious opportunity to use a wide range of laboratory techniques improving my skills as junior researcher. Also, I will have the fundamental chance to use for this project, state-of-the-art hi-tech equipment.

Becoming part of the research community of a nationally and internationally institute such as the UMC Utrecht will be a honor and will give me a unique and amazing opportunity for my future professional profile as scientist. Living for a several years in Netherlands would obviously offer me the chance to learn the Dutch language and keep practicing the English one, joining an international university.

I really wish to be selected for this position for contributing successfully with my research to the work of your group, in pursuing your scientific goals that will benefit the University of Utrecht and its academic community.
Thank you very much for your support and consideration,

Best Regards,
XXX
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Best Regards is only suitable for informal letters to your friends.

The more standard ending is
Yours sincerely
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It is too long; it can be whittled down a bit:

Dear Dr. XXX

I am interested in the PhD position with the Bacterial Immune Evasion group at the Department of Medical Microbiology at UMC Utrecht. I received my Master’s in Functional Genomics at the University of Trieste in March 2014, and I am confident my academic background and research experience would allow me to contribute positively to your research into the biological functions of streptococcal polysaccharides in host-pathogen interactions.

In one of my classes, Molecular Biology of the Cell, taught by Marco Scocchi, I discovered the fascinating world of bacterial pathogens. I subsequently received an Erasmus placement scholarship for a 7-month training period at the Centre for Biotechnology and Biomedicine in Leipzig. Under Ralf Hoffmann, I was involved in research elucidating proline-rich antimicrobial peptides mechanisms of action and identifying their potential intracelluar targets. The resulting thesis provided insight into the ability of these antimicrobial peptides to kill bacteria by blocking in vivo protein synthesis.

This experience reinforced my appreciation for microbiology in light of the increasing global threat of bacterial multi-drug resistance. It also allowed me to broaden my skills relevant to biology and biomedicine, as well as develop my abilities to work independently, take initiative in planning and organizing tasks, and assume responsibility for problems that arise.

I am very interested in working on host-pathogen interactions for their impact on global health. With bacterial and other infectious diseases becoming potential threats, antibiotic and vaccine research is a critical area. I have explored your web page, and your program seems like an excellent fit for me because of its emphasis on mechanisms of bacterial pathogenesis. Besides designing more effective pharmacological interventions and vaccine strategies, what I find very impelling is the ambition to discover the detailed functions of streptococcal polysaccharides, from the elucidation of their biosynthesis pathway to the understanding of the key role they play in host-pathogen interactions.

At UMC Utrecht, I would be able to employ a wide range of laboratory techniques and cutting-edge equipment to expand my skills as a researcher. Living in The Netherlands would also obviously offer me the chance to learn the Dutch language as well as maintain my English. Becoming part of the research community of your internationally respected institute would be a honor and a unique opportunity for my future professional career.

Thank you very much for your consideration.

Best regards,

XXX
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Comments  
Thank you very much Clive!
Try out our live chat room.
It looks very good MisterMicawber. Thank you very much Emotion: smile Do you think that the letter is ok?