+0
Hi everyone,

1) Cleavage of spectrin can lead to cell shrinkage, membrane blebbing and the formation of apoptotic bodies. Nevertheless, two genes encoding two subunits of spectrin show significant up-regulation.

2) Cleavage of spectrin can lead to cell shrinkage, membrane blebbing and the formation of apoptotic bodies. Despite this, two genes encoding two subunits of spectrin show significant up-regulation.

which one is better?

Thank you!
+0
HI,

I prefer #1. In #2, the reader has to hesitate briefly to consider what 'this' refers to.

Clive
Comments  
Thanks for your help!