I know that a lot of the time that "Of course" at the start of a sentence will be followed by a comma; however, if it comes at the end of the sentence, should a comma come before it?
1) It was obvious that I win of course
2) That's the point of course
And so on...
But it doesn't take the comma if you're using it emphatically. Do I think Obama has a chance to win the White House?! Of course I think he does!
I would definitely use it before the "of course" in your two examples.
People are waiting to help.