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Hi

Be on the lookout for such people and send them running!

--- Does "send them running" mean "get rid of them"?
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Depends on the context. It could also mean the opposite.

Your friend has started a new business, and wants you to send him some customers/prospects.
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Hi

I changed this sentence a little bit.

Be on the lookout for (something negative) and be ready to send it running!

--- In this case I think it means "get rid of it".

Thanks
Newguest I changed this sentence a little bit.
Would you believe, "A lot!"? Emotion: surprise
Hi

I didn't realize it was so important in this case. I thought the phrase "send sth running" has got only one meaning.

Thanks
Students: We have free audio pronunciation exercises.
There's another expression, "Send them/him packing," which is only negative. Emotion: smile

These expressions are commonly used in regard to people, so when we apply them to "things," it's usually a case of "personification."