Can pain 'take off' or does it make no sense?

For example:

"My back pain took off again. I need to lie down." I know that I can use 'kick off' or 'play up', but I'm not sure about 'take off'.

Thank you.


I always use "My back (pain) is acting up again".

Your choices are understandable, but unusual where I live.



Thank you. I forgot about ‘act up’.🤦🏼‍♀️