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"Leave" and "depart"

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leave is much more common.

depart is often in a more dramatic context.

Clive

+1
Best English

"Leave" and "depart"

"depart" is more formal and more often related to travel by commercial transportation. For example, at airports or train stations we see signs like "arrivals" and "departures" and we can take a look at the arrivals and departures board, but if we're going somewhere in our own cars, we say that we're leaving at a certain time, not "departing".

CJ