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what does "nervous wreck" mean? Does it mean "very uneasy"?

Context:

Reporting in the journal Neuron, a team of geneticists in the College of Agricultural and Life Sciences reveal the role of a gene in fruit flies called "nervous wreck" that prevents synapses from overgrowing by damping the effects of a pro-growth signal. Mutations in a human version of "nervous wreck" have been linked to a severe genetic developmental disability, and these findings may eventually help scientists develop treatments for this and other neurological disorders.
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Hi,

It seems to me that the answer to your question is in the text you posted:
NL888 ...reveal the role of a gene in fruit flies called "nervous wreck" that prevents synapses from overgrowing by damping the effects of a pro-growth signal...
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Search Yahoo with:
"nervous wreck" dictionary
and you will find:
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also : a person or animal of broken constitution, health, or spirits <he's a nervous wreck>

M-W Dictionary
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but I agree with Tanit that in the scientific contexts you should probably use the definition in that article.
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Comments  
Thank for replying.

Yes, it is quite clear in that scientific context. I think it has been used humorously there.

Is it (nervous wreck) close to "nerve cell growth terminator"?
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